Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 6/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.30 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27244339 | 1.00 | AHR (0.35) | AHRCYP1A2CYP3A4EEDMAP3K5 | |
| SCHEMBL27266398 | 1.00 | AHR (0.35) | AHRCYP1A2CYP3A4EEDMAP3K5 | |
| SCHEMBL30972574 | 0.92 | AHR (0.33) | AHRCYP1A2CYP3A4EEDMAP3K5 | |
| SCHEMBL27265902 | 0.88 | AHR (0.46) | AHRCYP1A2CYP3A4EEDRBBP4 | |
| SCHEMBL27244311 | 0.88 | AHR (0.46) | AHRCYP1A2CYP3A4EEDRBBP4 | |
| SCHEMBL27244330 | 0.88 | AHR (0.46) | AHRCYP1A2CYP3A4EEDRBBP4 | |
| SCHEMBL27266414 | 0.87 | CYP1A2 (0.34) | AHRCYP1A2CYP3A4EEDPTGDR2 | |
| SCHEMBL27244334 | 0.87 | CYP1A2 (0.34) | AHRCYP1A2CYP3A4EEDPTGDR2 | |
| SCHEMBL27266408 | 0.87 | CYP1A2 (0.34) | AHRCYP1A2CYP3A4EEDPTGDR2 | |
| SCHEMBL27244355 | 0.87 | CYP1A2 (0.33) | AHRCYP1A2CYP3A4EEDMAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107555-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2024-05-23 | — | — | WO | disclosed |