Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27266401 | 0.87 | AHR (0.35) | CYP1A2CYP3A4AHREEDMAP3K5 | |
| SCHEMBL27244339 | 0.87 | AHR (0.35) | CYP1A2CYP3A4AHREEDMAP3K5 | |
| SCHEMBL27266398 | 0.87 | AHR (0.35) | CYP1A2CYP3A4AHREEDMAP3K5 | |
| SCHEMBL27265902 | 0.85 | AHR (0.46) | CYP1A2CYP3A4AHREED | |
| SCHEMBL27244311 | 0.85 | AHR (0.46) | CYP1A2CYP3A4AHREED | |
| SCHEMBL27244330 | 0.85 | AHR (0.46) | CYP1A2CYP3A4AHREED | |
| SCHEMBL30972574 | 0.85 | AHR (0.33) | CYP1A2CYP3A4AHREEDMAP3K5 | |
| SCHEMBL27266394 | 0.83 | AHR (0.34) | CYP1A2CYP3A4AHREED | |
| SCHEMBL27244334 | 0.82 | CYP1A2 (0.34) | CYP1A2CYP3A4AHREED | |
| SCHEMBL27266408 | 0.82 | CYP1A2 (0.34) | CYP1A2CYP3A4AHREED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199608-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199608-A1 | AHR AGONISTS | AHR, ARNT, RORC | CYP1A2 176/4885CYP3A4 567/4885AHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.