Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 8/20 | 0.32 |
| ▸ | CPT2 | P23786 | 7/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726018 | 0.98 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL10291014 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL2728672 | 0.92 | NAA50 (0.34) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL6468356 | 0.92 | NAA50 (0.34) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL2728674 | 0.92 | NAA50 (0.34) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL2726344 | 0.91 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1PKMNAA50POLB | |
| SCHEMBL2728191 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2TRPV1PKMNAA50POLB | |
| SCHEMBL2727188 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2TRPV1NAA50POLBCPT1A | |
| SCHEMBL6466803 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1PKMKDM4ENAA50 | |
| SCHEMBL2725512 | 0.90 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1PKMKDM4ENAA50 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |