Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168226 | 0.93 | KMT2A (0.39) | KMT2ASMN1; SMN2HRH3GNAI3GNAO1 | |
| SCHEMBL24480413 | 0.88 | KMT2A (0.33) | KMT2ASMN1; SMN2CHRM2CHRM3HRH3 | |
| SCHEMBL27289186 | 0.88 | KMT2A (0.38) | KMT2ATLR9TLR7ACHE | |
| SCHEMBL2633463 | 0.85 | KMT2A (0.39) | KMT2ASMN1; SMN2HRH3ACHETSHR | |
| SCHEMBL14996489 | 0.85 | ALDH1A1 (0.38) | SMN1; SMN2HRH3TSHR | |
| SCHEMBL27291235 | 0.84 | KMT2A (0.41) | KMT2ASMN1; SMN2TLR9TLR7ACHE | |
| SCHEMBL24481348 | 0.84 | TSHR (0.33) | TSHR | |
| SCHEMBL24480850 | 0.84 | TSHR (0.32) | CHRM2CHRM3TSHR | |
| SCHEMBL23269619 | 0.83 | KMT2A (0.51) | KMT2ASMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL1160925 | 0.83 | KMT2A (0.51) | KMT2ASMN1; SMN2HRH3GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |