Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27291235 | 0.88 | KMT2A (0.41) | KMT2AACHETLR7 | |
| SCHEMBL25924745 | 0.87 | KMT2A (0.32) | KMT2AACHE | |
| SCHEMBL27289186 | 0.85 | KMT2A (0.38) | KMT2AACHETLR7 | |
| SCHEMBL26047959 | 0.82 | KMT2A (0.46) | KMT2AACHETLR7 | |
| SCHEMBL2633461 | 0.81 | KMT2A (0.36) | KMT2A | |
| SCHEMBL25001381 | 0.80 | TSHR (0.41) | — | |
| SCHEMBL26748104 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL18551162 | 0.78 | KMT2A (0.50) | KMT2AACHETLR7 | |
| SCHEMBL2633463 | 0.78 | KMT2A (0.39) | KMT2AACHE | |
| SCHEMBL15088302 | 0.78 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |