SCHEMBL25924745

SCHEMBL25924745

CCN1CCN(C2CCC3(CC2)CCN(CC2CCN(I)CC2)CC3)CC1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27268142 0.87 KMT2A (0.37) KMT2AACHE
SCHEMBL24475309 0.79 ACHE (0.42) ACHE
SCHEMBL27267808 0.79 ACHE (0.42) ACHE
SCHEMBL29317324 0.78 NCF1 (0.33)
SCHEMBL26047959 0.77 KMT2A (0.46) KMT2AACHE
SCHEMBL27269608 0.77
SCHEMBL27291235 0.76 KMT2A (0.41) KMT2AACHE
SCHEMBL27289186 0.76 KMT2A (0.38) KMT2AACHE
SCHEMBL2633461 0.76 KMT2A (0.36) KMT2A
SCHEMBL23173752 0.76 ACHE (0.42) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109892-A1 COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 海思科医药集团股份有限公司 2023-06-22 WO disclosed