Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 10/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527304 | 0.81 | CYP19A1 (0.50) | CYP17A1CYP3A4CYP19A1VCAM1MAPT | |
| SCHEMBL9198545 | 0.79 | CYP17A1 (0.52) | CYP17A1CYP19A1 | |
| SCHEMBL9190479 | 0.75 | CYP17A1 (0.47) | CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL9194817 | 0.74 | CYP17A1 (0.50) | CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL9523782 | 0.74 | CYP19A1 (0.60) | CYP17A1CYP3A4CYP19A1ALDH1A1MAPT | |
| SCHEMBL9727815 | 0.74 | CYP17A1 (0.47) | CYP17A1CYP19A1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8973344 | 0.74 | CYP17A1 (0.71) | CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL9664909 | 0.74 | CYP17A1 (0.57) | CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL11361986 | 0.72 | CYP17A1 (0.62) | CYP17A1CYP3A4CYP19A1ALDH1A1MAPT | |
| SCHEMBL8973924 | 0.71 | CYP17A1 (0.75) | CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022184-C | Process for preparing (1 H-imidzol-1-ylmethyl) substituted benzotriazole derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1993-09-22 | — | — | CN | disclosed |
| CN-88103408-A | Process for preparing (1H-oxazol-1-ylmethyl) substituted benzotriazole derivatives | — | 1988-12-14 | — | — | CN | disclosed |