Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.53 |
| ▸ | HTR1B | P28222 | 4/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.52 |
| ▸ | BCL2 | P10415 | 3/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.52 |
| ▸ | BAD | Q92934 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206887 | 0.90 | HTR1B (1.00) | HTR1BKCNA3TDP1SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL27274284 | 0.89 | HTR1B (0.96) | HTR1BKDM4EKCNA3TDP1KMT2A | |
| SCHEMBL10527536 | 0.85 | HTR1B (0.89) | HTR1BKCNA3TDP1SLC6A4HRH1 | |
| SCHEMBL6846750 | 0.83 | HTR1B (0.86) | HTR1BKCNA3TDP1SLC6A4HRH1 | |
| SCHEMBL10525289 | 0.83 | HTR1B (0.86) | HTR1BKCNA3TDP1SLC6A4HRH1 | |
| SCHEMBL10525194 | 0.83 | HTR1B (0.86) | HTR1BKCNA3TDP1SLC6A4HRH1 | |
| SCHEMBL30825865 | 0.81 | HTR1B (1.00) | HTR1BKDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL9523932 | 0.81 | HTR1B (1.00) | HTR1BKDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL29865493 | 0.81 | KDM4E (0.68) | HTR1BKDM4EALDH1A1HPGDKCNA3 | |
| SCHEMBL7279604 | 0.81 | HTR1B (0.65) | HTR1BKDM4EALDH1A1HPGDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020093-C | 1-phenyl -3-naphthalenyloxypropanamines | LILLY CO ELI (US) | 1993-03-17 | — | — | CN | disclosed |
| CN-88102018-A | 1-Phenyl-3-naphthyloxypropylamine | — | 1988-10-26 | — | — | CN | disclosed |