Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 12/20 | 1.00 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | HTR1D | P28221 | 2/20 | 0.59 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27274284 | 0.98 | HTR1B (0.96) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL10527536 | 0.94 | HTR1B (0.89) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL10525194 | 0.93 | HTR1B (0.86) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL6846750 | 0.93 | HTR1B (0.86) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL10525289 | 0.93 | HTR1B (0.86) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL9523932 | 0.90 | HTR1B (1.00) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL30825865 | 0.90 | HTR1B (1.00) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| Oxalic Acid SCHEMBL27269366 | 0.90 | HTR1B (0.81) | HTR1BKCNA3SLC6A4HRH1NR2E1 | |
| SCHEMBL9770352 | 0.88 | KCNA3 (0.81) | HTR1BKCNA3SLC6A4HRH1HTR1D | |
| SCHEMBL2177350 | 0.88 | HTR1B (0.78) | HTR1BKCNA3SLC6A4HRH1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| CN-1224426-A | 3-descladinose-2, 3-anhydroerythromycin derivatives | ABBOTT LAB (US) | 1999-07-28 | — | — | CN | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |
| CN-1020093-C | 1-phenyl -3-naphthalenyloxypropanamines | LILLY CO ELI (US) | 1993-03-17 | — | — | CN | disclosed |
| CN-88102018-A | 1-Phenyl-3-naphthyloxypropylamine | — | 1988-10-26 | — | — | CN | disclosed |
| US-4536503-A | Naphthoxyalkylamines and related compounds as antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0082005-A2 | Naphthoxyalkylamines and related compounds, their preparation and antiinflammatory compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-06-22 | — | — | EP | disclosed |