Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.50 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 11/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31129378 | 0.95 | IKZF2 (0.49) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL27271517 | 0.95 | IKZF2 (0.48) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL29927821 | 0.94 | IKZF2 (0.50) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL25133940 | 0.94 | IKZF2 (0.50) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL29132146 | 0.94 | IKZF2 (0.50) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL27271073 | 0.93 | IKZF2 (0.47) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL31129642 | 0.93 | IKZF2 (0.48) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL25134262 | 0.92 | CRBN (0.44) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL29928133 | 0.92 | CRBN (0.44) | IKZF2IKZF1CRBNIKZF3DDB1 | |
| SCHEMBL31129674 | 0.91 | IKZF2 (0.48) | IKZF2IKZF1CRBNIKZF3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112692-A1 | CASITAS B-LINEAGE LYMPHOMA PROTOONCOGENE B (CBL-B) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |