⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27271914 | 1.00 | — | — | |
| SCHEMBL22778538 | 1.00 | — | — | |
| SCHEMBL8742265 | 1.00 | — | — | |
| SCHEMBL21653690 | 0.85 | — | — | |
| SCHEMBL15744055 | 0.84 | — | — | |
| SCHEMBL3004250 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL21268628 | 0.80 | — | — | |
| SCHEMBL19750771 | 0.79 | — | — | |
| SCHEMBL23134489 | 0.79 | LMNA (0.38) | — | |
| SCHEMBL16474016 | 0.74 | SLC22A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247593-A1 | PYRROLOPYRIDINE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | disclosed |