Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949639 | 0.85 | TSHR (0.60) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL67864 | 0.85 | MAPK1 (0.60) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL68713 | 0.83 | TSHR (0.58) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL68181 | 0.83 | TSHR (0.58) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL899743 | 0.83 | TSHR (0.58) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL9191570 | 0.83 | MAPK1 (0.58) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6377973 | 0.83 | MAPK1 (0.58) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL28960511 | 0.81 | TSHR (0.56) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL405093 | 0.80 | TSHR (0.55) | MAPK1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL1663911 | 0.80 | NOS3 (0.63) | MAPK1TSHRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1016175-B | Imidazoquinoline antithrombin cardiotonic agents | BRISTOL MYERS CO (US) | 1992-04-08 | — | — | CN | disclosed |
| CN-86102747-A | The preparation method of imidazoquinoline antithombogehic cardiotonic agents | — | 1987-02-04 | — | — | CN | disclosed |