Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 6/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263739 | 0.86 | BCAT2 (1.00) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL19119395 | 0.85 | BCAT2 (0.76) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL23209156 | 0.82 | BCAT2 (0.72) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL265344 | 0.82 | HPGD (1.00) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL23267317 | 0.81 | BCAT2 (0.70) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL263943 | 0.80 | KDM4E (1.00) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL264414 | 0.78 | BCAT2 (0.65) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL12318281 | 0.78 | PDPK1 (0.70) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL25908842 | 0.77 | PDPK1 (1.00) | BCAT2HPGDKDM4ELMNAGAA | |
| SCHEMBL30987724 | 0.76 | BCAT2 (0.44) | BCAT2HPGDKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133560-A1 | IMIDAZO[1,2-A]PYRIDINE AND IMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS MLLT1 AND MLLT3 INHIBITORS | DARK BLUE THERAPEUTICS LTD (GB) | 2024-06-27 | — | — | WO | disclosed |