Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10091151 | 1.00 | ESR2 (0.46) | ESR2LIPEKDM1ARCOR1DRD4 | |
| SCHEMBL10091161 | 0.95 | ESR2 (0.42) | ESR2LIPEKDM1ARCOR1DRD4 | |
| SCHEMBL10091171 | 0.90 | CHRM4 (0.40) | ESR2LIPEKDM1ARCOR1DRD4 | |
| SCHEMBL29878889 | 0.90 | HTR2C (0.47) | KDM1ARCOR1DRD4HTR2CHTR2A | |
| SCHEMBL1515236 | 0.90 | HTR2C (0.47) | KDM1ARCOR1DRD4HTR2CHTR2A | |
| SCHEMBL6455875 | 0.83 | HTR2A (0.39) | KDM1ARCOR1HTR2CHTR2AHTR2B | |
| SCHEMBL6455880 | 0.83 | HTR2A (0.39) | KDM1ARCOR1HTR2CHTR2AHTR2B | |
| Ethylamine SCHEMBL28128862 | 0.83 | HTR2A (0.51) | KDM1ARCOR1DRD4HTR2CHTR2A | |
| SCHEMBL777204 | 0.82 | HDAC4 (0.52) | KDM1ARCOR1DRD4HTR2CHTR2A | |
| SCHEMBL353609 | 0.82 | HDAC4 (0.47) | KDM1ARCOR1DRD4HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023249875-A1 | SUBSTITUTED PYRROLIDINYL AND PIPERIDINYL COMPOUNDS AND RELATED METHODS OF TREATMENT | ALKERMES, INC. (US) | 2023-12-28 | — | — | WO | disclosed |