Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455880 | 1.00 | HTR2A (0.39) | HTR2AHTR2CHTR2BTRPV1KDM1A | |
| SCHEMBL10091161 | 0.85 | ESR2 (0.42) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL6456776 | 0.84 | TAAR1 (0.41) | HTR2CKDM1A | |
| SCHEMBL6456781 | 0.84 | TAAR1 (0.41) | HTR2CKDM1A | |
| SCHEMBL6463935 | 0.83 | SLC6A2 (0.33) | — | |
| SCHEMBL6463939 | 0.83 | SLC6A2 (0.33) | — | |
| SCHEMBL27273287 | 0.83 | ESR2 (0.46) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL10091151 | 0.83 | ESR2 (0.46) | HTR2AHTR2CHTR2BKDM1ARCOR1 | |
| SCHEMBL6456896 | 0.83 | FASN (0.38) | — | |
| SCHEMBL6456894 | 0.83 | FASN (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |