Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL2586200 | 0.81 | SLC7A5 (0.35) | CTSCSCN3ASCN9AHTR2CHTR2B | |
| Histidine SCHEMBL27902238 | 0.81 | SLC7A5 (0.35) | CTSCSCN3ASCN9AHTR2CHTR2B | |
| Histidine SCHEMBL2586203 | 0.81 | SLC7A5 (0.35) | CTSCSCN3ASCN9AHTR2CHTR2B | |
| D-Histidine SCHEMBL11606906 | 0.81 | SLC7A5 (0.35) | CTSCSCN3ASCN9AHTR2CHTR2B | |
| Histidine SCHEMBL10455821 | 0.81 | SLC7A5 (0.34) | CTSCHTR2CHTR2B | |
| Histidine SCHEMBL9719668 | 0.81 | SLC7A5 (0.34) | CTSCHTR2CHTR2B | |
| Histidine SCHEMBL3490081 | 0.80 | CYP3A4 (0.32) | CTSC | |
| Histidine SCHEMBL790243 | 0.80 | CYP3A4 (0.32) | CTSC | |
| Histidine SCHEMBL1675273 | 0.80 | CYP3A4 (0.32) | CTSC | |
| Histidine SCHEMBL3088582 | 0.80 | CYP3A4 (0.32) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | claimed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | claimed |
| CN-105949280-A | Preparation method of Taltirelin and intermediate thereof | 吉尔生化（上海）有限公司 | 2016-09-21 | — | — | CN | disclosed |
| CN-103665170-A | Peptide therapeutic conjugates and uses thereof | ANGIOCHEM INC | 2014-03-26 | — | — | CN | disclosed |
| CN-102348723-A | Peptide therapeutic agent conjugates and uses thereof | ANGIOCHEM INC | 2012-02-08 | — | — | CN | disclosed |
| CN-1214040-C | Peptide derivatives having thiazolyl-alanine residues | SHIONOGI & CO (JP) | 2005-08-10 | — | — | CN | disclosed |
| CN-1235610-A | Peptide derivatives having thiazolyl-alanine residues | SHIONOGI & CO (JP) | 1999-11-17 | — | — | CN | disclosed |
| CN-1020457-C | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | TANABE SEIYAKU CO (JP) | 1993-05-05 | — | — | CN | disclosed |
| CN-85105655-A | Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof | — | 1987-01-28 | — | — | CN | disclosed |