Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31071511 | 1.00 | MGLL (0.61) | MGLLFAAHABHD6CYP2D6PLA2G7 | |
| SCHEMBL22488091 | 1.00 | MGLL (0.61) | MGLLFAAHABHD6CYP2D6PLA2G7 | |
| SCHEMBL29616461 | 0.89 | MGLL (0.65) | MGLL | |
| SCHEMBL22462769 | 0.89 | MGLL (0.65) | MGLL | |
| SCHEMBL24095482 | 0.88 | MGLL (0.75) | MGLL | |
| SCHEMBL24095479 | 0.84 | MGLL (0.61) | MGLL | |
| SCHEMBL21723274 | 0.84 | MGLL (0.63) | MGLL | |
| SCHEMBL21730744 | 0.84 | MGLL (0.63) | MGLL | |
| SCHEMBL21723273 | 0.84 | MGLL (0.63) | MGLL | |
| SCHEMBL21730857 | 0.80 | MGLL (0.75) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837263-B1 | NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2024-07-03 | — | — | EP | disclosed |