Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.83 |
| ▸ | ARG2 | P78540 | 4/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL31545754 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL272788 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL28324668 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL30002814 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL8201264 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL5685994 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL31277390 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL22129529 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL22129528 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPPMP22 | |
| Lysine SCHEMBL9200668 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2206 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3585362-B1 | COMPOSITION FOR CONTROLLED RELEASE OF PHYSIOLOGICALLY ACTIVE SUBSTANCES AND PROCESS FOR ITS PREPARATION | BALCHEM ITALIA S R L (IT) | 2026-04-01 | — | — | EP | claimed |
| US-12557829-B2 | Liquid-phase, supplementary feed composition containing coenzyme Q10 | YU HYO GYOUNG (KR) | 2026-02-24 | — | — | US | claimed |
| US-20260033516-A1 | ADDITIVE COMPOSITION FOR RUMINANT FEEDS | AJINOMOTO CO., INC. (JP) | 2026-02-05 | — | — | US | claimed |
| CN-120188855-A | Cotton source feed for fattening stage of pigs and preparation method thereof | 石河子大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120036437-A | Complete feed for improving growth performance of secondary fattening pigs and application thereof | 湖南金汇龙科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119859160-A | Functional caprolactam and intrinsic flame-retardant nylon material, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2025-04-22 | — | — | CN | claimed |
| CN-119837188-A | Application of epigallocatechin gallate in improving growth performance of broiler chickens and feed | 沈阳农业大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119707769-A | Method for preparing caprolactam by using fermentation liquor containing lysine, lysine or lysine salt as raw materials | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119708463-A | Polymer antibacterial agent, antibacterial nylon material, and preparation methods and applications thereof | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-115888798-B | Catalyst with embedded metal particles, preparation method and application of catalyst in catalytic synthesis of pentanediamine | 郑州中科新兴产业技术研究院 | 2025-02-14 | — | — | CN | claimed |
| EP-1424012-A2 | Process for making granular L-lysine feed supplement | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2004-06-02 | — | — | EP | claimed |
| US-20040067890-A1 | Ascorbic acid salts of organic bases with enhanced bioavailability for synergictic anti-aging and skin protective cosmetic compositions | GUPTA SHYAM K (US) | 2004-04-08 | — | — | US | claimed |
| US-20030065239-A1 | Non-hazardous basic neutralization of aldehydes | ETHICON, INC. | 2003-04-03 | — | — | US | claimed |
| CN-1269980-A | Preparation of granular L-lysine additives for forage | EATCH DENNIS MIDLAND CO (US) | 2000-10-18 | — | — | CN | claimed |
| US-6017555-A | COMPRISING ADDING A MATERIAL CONTAINING L-LYSINE TO AN L-LYSINE FERMENTATION BROTH OR A FRACTION OF AN L-LYSINE FERMENTATION BROTH | ARCHER DANIELS MIDLAND COMPANY (US) | 2000-01-25 | — | — | US | claimed |
| EP-0923878-A2 | Process for making granular L-lysine feed supplement | ARCHER-DANIELS-MIDLAND COMPANY (US) | 1999-06-23 | — | — | EP | claimed |
| WO-1998054351-A1 | A COMBINED PROCESS FOR THE PRODUCTION OF LYSINE AND ITS SALTS AND OF A FURTHER WEAK ACID AND A SALT THEREOF | AMYLUM BELGIUM N.V. (BE) | 1998-12-03 | — | — | WO | claimed |
| CN-1063311-A | The method for preparing granular L-lysine | ARCHER DANIELS MIDLAND CO (US) | 1992-08-05 | — | — | CN | claimed |
| US-5133976-A | Biosynthesis | RHONE-POULENC SANTE (FR) | 1992-07-28 | — | — | US | claimed |
| EP-0491638-A2 | Method of making granulated L-lysine | ARCHER-DANIELS-MIDLAND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |