Lysine

Lysine

SCHEMBL22129529

NCCCCC(N)C(=O)O.O=S(=O)(O)O.[Fe]

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.80
ARG2 P78540 4/20 0.50
ARG1 P05089 3/20 0.50
RNPEP Q9H4A4 1/20 0.48
PMP22 Q01453 1/20 0.46
NOS2 P35228 4/20 0.44
CYP1A2 P05177 3/20 0.44
NOS3 P29474 2/20 0.44
NOS1 P29475 2/20 0.44
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
CPB2 Q96IY4 1/20 0.44
GLA P06280 1/20 0.44
NFKB1 P19838 1/20 0.44
APEX1 P27695 1/20 0.44
CYP2C19 P33261 1/20 0.44
THRB P10828 1/20 0.44
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL28611534 1.00 GSR (0.80) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL272788 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL272789 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL31545754 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL8201264 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL28324668 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL30002814 0.98 GSR (0.83) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL9200668 0.96 GSR (0.80) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL5685994 0.96 GSR (0.80) GSRARG2ARG1RNPEPPMP22
Lysine SCHEMBL31277390 0.96 GSR (0.80) GSRARG2ARG1RNPEPPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116846-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSINE SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2026-04-30 US disclosed
US-12497350-B2 Preparation of a lysinate compound from an aqueous lysine solution PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2025-12-16 US disclosed
EP-3670494-B1 PRODUCTION OF LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2023-06-14 EP disclosed
US-20220024856-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2022-01-27 US disclosed
EP-3898576-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION Phytobiotics Futterzusatzstoffe GmbH (DE) 2021-10-27 EP disclosed
WO-2020126647-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION PHYTOBIOTICS FUTTERZUSATZSTOFFE GMBH (DE) 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024856-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSIN SOLUTION LTN1, LCT, LPXN GSR 4803/4885ARG2 924/4885ARG1 248/4885
US-20260116846-A1 PREPARATION OF A LYSINATE COMPOUND FROM AN AQUEOUS LYSINE SOLUTION SLC6A9, SLC6A19, SLC39A14 GSR 4531/4885ARG2 1046/4885ARG1 84/4885
US-12497350-B2 Preparation of a lysinate compound from an aqueous lysine solution KDM5A, KDM5B, KDM5C GSR 4835/4885ARG2 1019/4885ARG1 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.