SCHEMBL27280461

SCHEMBL27280461

Cn1cc(-c2cc3c(N4CC5CCC(C4)N5C(=O)OC(C)(C)C)ncnc3[nH]2)cn1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KIT P10721 19/20 0.52
▸ RET P07949 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30669825 1.00 KIT (0.52) KITRET
SCHEMBL30669810 0.89 KIT (0.51) KIT
SCHEMBL29772725 0.89 KIT (0.51) KIT
SCHEMBL29772784 0.86 KIT (0.55) KIT
SCHEMBL24615215 0.86 KIT (0.55) KIT
SCHEMBL27280129 0.86 JAK1 (0.48) KITRET
SCHEMBL24615536 0.86 JAK1 (0.48) KITRET
SCHEMBL30669778 0.86 JAK1 (0.48) KITRET
SCHEMBL24615304 0.85 KIT (0.49) KIT
SCHEMBL24615480 0.83 KIT (0.52) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547674-A1 TYK2 INHIBITORS Biogen MA Inc. (US) 2025-05-07 — — EP disclosed
CN-119731186-A TYK2 inhibitors 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN disclosed
WO-2024006493-A1 TYK2 INHIBITORS BIOGEN MA INC. (US) 2024-01-04 — — WO disclosed
WO-2024006493-A1 TYK2 INHIBITORS BIOGEN MA INC. (US) 2024-01-04 — — WO disclosed
EP-4274832-A1 TYK2 INHIBITORS Biogen MA Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150446-A1 TYK2 INHIBITORS BIOGEN MA INC. (US) 2022-07-14 — — WO disclosed
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