Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 5/20 | 0.48 |
| ▸ | RET | P07949 | 3/20 | 0.48 |
| ▸ | KIT | P10721 | 6/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | TYK2 | P29597 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615536 | 1.00 | JAK1 (0.48) | JAK1RETKITGPR119TBK1 | |
| SCHEMBL27280129 | 1.00 | JAK1 (0.48) | JAK1RETKITGPR119TBK1 | |
| SCHEMBL29772793 | 0.87 | JAK2 (0.52) | JAK1KITAURKAAURKBINCENP | |
| SCHEMBL24615337 | 0.87 | JAK2 (0.52) | JAK1KITAURKAAURKBINCENP | |
| SCHEMBL30669825 | 0.86 | KIT (0.52) | RETKIT | |
| SCHEMBL27280461 | 0.86 | KIT (0.52) | RETKIT | |
| SCHEMBL24615535 | 0.86 | AURKA (0.40) | JAK1KITTBK1AURKAAURKB | |
| SCHEMBL20920004 | 0.85 | KIT (0.60) | RETKITGPR119 | |
| SCHEMBL24615619 | 0.84 | JAK1 (0.56) | JAK1JAK2TYK2 | |
| SCHEMBL30669813 | 0.84 | JAK1 (0.46) | JAK1RETKITGPR119HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119731186-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |