Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725910 | 0.84 | CFTR (0.43) | CFTRKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL2724737 | 0.81 | CFTR (0.39) | CFTREEF2KTUBB4ATUBBTUBA3C | |
| SCHEMBL2726268 | 0.78 | CFTR (0.37) | CFTRCHEK2EEF2KRAB9ATUBB4A | |
| SCHEMBL3353479 | 0.76 | CFTR (0.43) | CFTRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1932923 | 0.71 | CHEK2 (0.38) | KDM4AKDM4BKDM5CKDM5BCHEK2 | |
| SCHEMBL3347772 | 0.70 | GLRA3 (0.44) | CFTRKDM4EPIK3CB | |
| SCHEMBL2726900 | 0.70 | CFTR (0.34) | CFTRCHEK2EEF2KRAB9AIRAK4 | |
| SCHEMBL1429349 | 0.68 | KDM4A (0.39) | KDM4AKDM4BKDM5CKDM5BKDM4E | |
| SCHEMBL2728043 | 0.67 | KDM4B (0.39) | KDM4AKDM4BKDM5CKDM5BPOLB | |
| SCHEMBL2726265 | 0.66 | TGFBR1 (0.38) | CFTRRAB9AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |