Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CREB1 | P16220 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10870541 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL27280517 | 0.82 | KDM4E (0.45) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6241692 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6239909 | 0.78 | KDM4E (0.45) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6243266 | 0.78 | GAA (0.43) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27290345 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6242074 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7074007 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28409938 | 0.73 | MAPT (0.50) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10007918 | 0.73 | KDM4E (0.58) | KDM4EMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1007153-B | PREPN. OF BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGY ACTIVITY | WARNER LAMBERT CO (US) | 1990-03-14 | — | — | CN | disclosed |
| CN-85109587-A | Have the new benzothiophene kind of antiallergic activity and the preparation method of benzofuran compounds | — | 1986-12-17 | — | — | CN | disclosed |