Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432934 | 0.89 | RXRA (0.47) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9433730 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27280515 | 0.82 | KDM4E (0.44) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9433482 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9432759 | 0.80 | EDNRA (0.54) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6239909 | 0.79 | KDM4E (0.45) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27280518 | 0.79 | NR4A2 (0.44) | KDM4ENR4A2ALDH1A1MEN1KMT2A | |
| SCHEMBL9825828 | 0.77 | PTGS1 (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6243266 | 0.77 | GAA (0.43) | KDM4ENR4A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27290346 | 0.76 | KLKB1 (0.45) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1007153-B | PREPN. OF BENZOTHIOPHENES AND BENZOFURANS HAVING ANTIALLERGY ACTIVITY | WARNER LAMBERT CO (US) | 1990-03-14 | — | — | CN | disclosed |
| CN-85109587-A | Have the new benzothiophene kind of antiallergic activity and the preparation method of benzofuran compounds | — | 1986-12-17 | — | — | CN | disclosed |