Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287322 | 1.00 | TSHR (0.48) | TSHRTDP1ALDH1A1 | |
| SCHEMBL27280584 | 1.00 | TSHR (0.48) | TSHRTDP1ALDH1A1 | |
| SCHEMBL27280932 | 0.77 | — | — | |
| SCHEMBL27864231 | 0.77 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| SCHEMBL20210214 | 0.74 | TDP1 (0.50) | TDP1 | |
| SCHEMBL27280917 | 0.74 | — | — | |
| SCHEMBL27280918 | 0.74 | — | — | |
| SCHEMBL27287205 | 0.74 | — | — | |
| SCHEMBL2834285 | 0.73 | — | — | |
| SCHEMBL27280586 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |