⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834285 | 1.00 | — | — | |
| SCHEMBL21604235 | 0.77 | — | — | |
| SCHEMBL27280431 | 0.77 | — | — | |
| SCHEMBL7676852 | 0.76 | — | — | |
| SCHEMBL27280932 | 0.75 | — | — | |
| SCHEMBL27287322 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL27280584 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL27280583 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL13660465 | 0.71 | — | — | |
| SCHEMBL4155536 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |