Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 11/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20326324 | 0.88 | TEAD1 (0.39) | TEAD1BTK | |
| SCHEMBL21741246 | 0.77 | TEAD1 (0.36) | TEAD1BTKEGFR | |
| SCHEMBL21565892 | 0.74 | TEAD1 (0.36) | TEAD1BTK | |
| SCHEMBL23735830 | 0.74 | TEAD1 (0.39) | TEAD1BTK | |
| SCHEMBL17897298 | 0.71 | PIK3C3 (0.36) | — | |
| SCHEMBL20314874 | 0.71 | TEAD1 (0.36) | TEAD1BTK | |
| SCHEMBL23308477 | 0.70 | TEAD1 (0.37) | TEAD1 | |
| SCHEMBL23308415 | 0.69 | JAK3 (0.38) | TEAD1BTK | |
| SCHEMBL20314879 | 0.69 | JAK3 (0.38) | TEAD1BTK | |
| SCHEMBL23569900 | 0.69 | JAK3 (0.38) | TEAD1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790886-B1 | KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2024-06-26 | — | — | EP | disclosed |