Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.43 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 14/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27280799 | 0.89 | JAK2 (0.54) | AURKAAURKBINCENPTPX2TBK1 | |
| SCHEMBL30726672 | 0.89 | JAK2 (0.54) | AURKAAURKBINCENPTPX2TBK1 | |
| SCHEMBL30726670 | 0.89 | JAK2 (0.54) | AURKAAURKBINCENPTPX2TBK1 | |
| SCHEMBL27280792 | 0.89 | JAK2 (0.54) | AURKAAURKBINCENPTPX2TBK1 | |
| SCHEMBL24615337 | 0.82 | JAK2 (0.52) | AURKAAURKBINCENPTPX2KIT | |
| SCHEMBL29772793 | 0.82 | JAK2 (0.52) | AURKAAURKBINCENPTPX2KIT | |
| SCHEMBL27280774 | 0.82 | KIT (0.45) | KIT | |
| SCHEMBL24615541 | 0.82 | AURKA (0.48) | AURKAAURKBINCENPTPX2TBK1 | |
| Hydrochloric Acid SCHEMBL29772761 | 0.81 | AURKA (0.47) | AURKAAURKBINCENPTPX2TBK1 | |
| SCHEMBL24615501 | 0.81 | TYK2 (0.55) | AURKAAURKBINCENPTPX2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006493-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2024-01-04 | — | — | WO | disclosed |