Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27279317 | 0.95 | MAPT (0.45) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279312 | 0.95 | MAPT (0.45) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279306 | 0.90 | MAPT (0.47) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279296 | 0.90 | MAPT (0.41) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279338 | 0.89 | MAPT (0.46) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279420 | 0.89 | MAPT (0.46) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279302 | 0.86 | MAPT (0.44) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279299 | 0.86 | MAPT (0.44) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27280962 | 0.83 | MAPT (0.52) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL27279287 | 0.81 | MAPT (0.46) | MAPTNPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209010-A1 | PRODRUGS OF AZO COMPOUNDS AND THEIR SALTS | AMNEAL PHARMACEUTICALS LLC | 2024-06-27 | — | — | US | disclosed |
| US-20240209010-A1 | PRODRUGS OF AZO COMPOUNDS AND THEIR SALTS | AMNEAL PHARMACEUTICALS LLC | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240209010-A1 | PRODRUGS OF AZO COMPOUNDS AND THEIR SALTS | CYP11B1, CYP2C19, CYP11B2 | MAPT 2300/4885NPC1 407/4885HTT 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.