Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153213 | 0.94 | PIK3CD (0.44) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL13656171 | 0.92 | PIK3CD (0.42) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL14706856 | 0.89 | PIK3CD (0.45) | PIK3CDHRH3CYP2D6SMN1; SMN2GNAI3 | |
| SCHEMBL24940791 | 0.88 | PIK3CD (0.42) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL22318587 | 0.88 | PIK3CD (0.42) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL24841928 | 0.86 | PIK3CD (0.58) | PIK3CDHRH3CYP2D6SMN1; SMN2 | |
| SCHEMBL22305201 | 0.86 | PIK3CD (0.41) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL22302061 | 0.84 | PIK3CD (0.40) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL24940792 | 0.84 | PIK3CD (0.40) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 | |
| SCHEMBL13656173 | 0.82 | PIK3CD (0.54) | PIK3CDHRH3CYP2D6SMN1; SMN2BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081311-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2024-04-18 | — | — | WO | disclosed |