Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24755017 | 0.86 | GNAI3 (0.48) | PIK3CDGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL27284401 | 0.86 | PIK3CD (0.45) | PIK3CDGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL27282015 | 0.86 | PIK3CD (0.45) | PIK3CDGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL27284398 | 0.86 | PIK3CD (0.45) | PIK3CDGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL12153213 | 0.84 | PIK3CD (0.44) | PIK3CDHRH3BIRC2CYP2D6SMN1; SMN2 | |
| SCHEMBL13656171 | 0.82 | PIK3CD (0.42) | PIK3CDHRH3BIRC2CYP2D6SMN1; SMN2 | |
| SCHEMBL22318587 | 0.82 | PIK3CD (0.42) | PIK3CDGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL24940792 | 0.79 | PIK3CD (0.40) | PIK3CDHRH3BIRC2CYP2D6SMN1; SMN2 | |
| SCHEMBL23716220 | 0.79 | PIK3CD (0.50) | PIK3CDHRH3CYP2D6SMN1; SMN2 | |
| SCHEMBL24992026 | 0.79 | PIK3CD (0.50) | PIK3CDHRH3CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160192-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |