Ethylene Glycol

Ethylene Glycol

SCHEMBL27282201

C=C(C)C(=O)OC(=O)C(=C)C.OCCO.OCCO.OCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.41
TDP1 Q9NUW8 4/20 0.39
HSD17B10 Q99714 1/20 0.39
TGFBR1 P36897 1/20 0.31
ELANE P08246 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL9875520 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTDP1HSD17B10
Ethylene Glycol SCHEMBL6342748 0.90 TDP1 (0.48) ALDH1A1TSHRTHRBTDP1HSD17B10
1,4-Butanediol SCHEMBL3748654 0.90 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTDP1HSD17B10
Alcohol SCHEMBL11226174 0.89 ALDH1A1 (0.50) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL15963 0.88 ALDH1A1 (0.61) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL28170047 0.88 ALDH1A1 (0.61) ALDH1A1TSHRTHRBTDP1HSD17B10
Di(Hydroxyethyl)Ether SCHEMBL27312004 0.85 TSHR (0.46) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL8953021 0.85 ALDH1A1 (0.58) ALDH1A1TSHRTHRBTDP1HSD17B10
Hydrochloric Acid SCHEMBL17099626 0.85 ALDH1A1 (0.58) ALDH1A1TSHRTHRBTDP1HSD17B10
SCHEMBL31589203 0.85 ALDH1A1 (0.58) ALDH1A1TSHRTHRBTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109771301-A A kind of mesoporous SiO of flakes2Nano-particle reinforcement dentistry composite resin and preparation method thereof 东华大学 2019-05-21 CN claimed
CN-105055374-B A kind of spacetabs type hydrochloric acid sarafloxacin microcapsules and preparation method thereof 山西沃德华兽生物技术有限公司 2017-11-03 CN claimed
CN-103340197-A Slow/controlled-release microcapsule pesticide and preparation method thereof UNIV CHINA AGRICULTURAL 2013-10-09 CN claimed
CN-103314056-A Hybrid silicone composition for light emitting device ABLESTIK SHANGHAI LTD 2013-09-18 CN claimed
CN-103304745-A Polymerizable flame retardant resin ZHEJIANG RONGTAI TECHNOLOGY ENTPR CO LTD 2013-09-18 CN claimed
CN-103211711-A Highly wear-resisting composite resin with high modulus for dental repair and preparation method thereof UNIV DONGHUA 2013-07-24 CN claimed
CN-103211712-A Nano-composite resin with low shrinking percentage for dental repair and preparation method thereof UNIV DONGHUA 2013-07-24 CN claimed
CN-103205226-A Solvent type acrylate pressure-sensitive adhesive, and preparation method and application thereof HUBEI AEROSPACE CHEMICAL TECHNOLOGY RES INST 2013-07-17 CN claimed
CN-102731704-A Method for preparing open-cell submicron porous polymer materials by miniemulsion template method UNIV ZHEJIANG 2012-10-17 CN claimed
CN-102702419-A Preparation method of montmorillonite-modified crosslinked acrylate-hybridized core-shell emulsion CAS GUANGZHOU CHEMISTRY CO LTD 2012-10-03 CN claimed
CN-1452639-A Methods for preparing of weatherability thermoplastic resin LG CHEN LTD (KR) 2003-10-29 CN claimed
CN-1394215-A Method for preparing methylmethacrylate-butadiene-styrene graft copolymer with excellent stress whitening resistance LG CHEMICAL LTD (KR) 2003-01-29 CN claimed
CN-1384123-A Synthesis of polymer and film of the polymer HIPRAY CO (US) 2002-12-11 CN claimed
CN-1382165-A Process for preparing optical quality polymers JOHNSON & JOHNSON VISION CARE (US) 2002-11-27 CN claimed
CN-1370204-A Flame-retardant UV and UV/moisture curable silicone compsns. LOCTITE CORP (US) 2002-09-18 CN claimed
CN-1088457-C Photochromic naphthopyran compounds PILKINGTON PLC (GB) 2002-07-31 CN claimed
CN-1300283-A Polymerizable hydrophilio ultraviolet light absorbing manomers PHARMACIA & UPJOHN BV (NL) 2001-06-20 CN claimed
CN-1270504-A Dental composite and adhesion promoter IVAN STANGEL (US) 2000-10-18 CN claimed
CN-1120335-A Photochromic naphthopyran compounds PILKINGTON PLC (GB) 1996-04-10 CN claimed
CN-1068126-A VINYL MONOMER COMPOSITIONS WITH ACCELERATED SURFACE CURE ROHM & HAAS (US) 1993-01-20 CN claimed