Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroquinone SCHEMBL27817865 | 0.91 | HPRT1 (0.45) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| Betanaphthol SCHEMBL27782405 | 0.88 | ALDH1A1 (0.42) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| Anthracene SCHEMBL27553379 | 0.88 | HPRT1 (0.48) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| SCHEMBL27782604 | 0.88 | KDM4E (0.41) | CYP1A2NQO1ALDH1A1ACHEHPGD | |
| Naphthalene SCHEMBL27290430 | 0.88 | HPRT1 (0.52) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| Phenol SCHEMBL28150296 | 0.87 | ALDH1A1 (0.47) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| Benz(B)Anthracene SCHEMBL27637885 | 0.86 | HPRT1 (0.47) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| SCHEMBL30928215 | 0.86 | HPRT1 (0.54) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| SCHEMBL21176632 | 0.86 | HPRT1 (0.54) | CYP1A2NQO1ALDH1A1MAPTLCK | |
| SCHEMBL2089665 | 0.86 | HPRT1 (0.54) | CYP1A2NQO1ALDH1A1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177133-A | Tetrahydronaphthalene compounds | ACTELION PHARMACEUTICALS LTD | 2011-09-07 | — | — | CN | disclosed |
| CN-100387576-C | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI CHEMICAL IND (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-1653032-A | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI CHEMICAL IND (JP) | 2005-08-10 | — | — | CN | disclosed |
| CN-1113874-C | Benzocycloalkylazolethione derivatives | SYNTEX INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1151735-A | Benzocycloalkylazolethione derivatives | SYNTEX INC (US) | 1997-06-11 | — | — | CN | disclosed |
| CN-1007727-B | PROCESS FOR THE PREPARATION OF TETRAHYDRONAPHTALINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1990-04-25 | — | — | CN | disclosed |
| CN-85107496-A | The method for preparing tetrahydronaphthalenderivatives derivatives | — | 1986-07-23 | — | — | CN | disclosed |