Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10240973 | 0.81 | MRGPRX4 (0.44) | MRGPRX4FFAR4CYP2C9MAPTKMT2A | |
| SCHEMBL11190301 | 0.79 | CA1 (0.44) | MRGPRX4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL11190308 | 0.79 | CA1 (0.44) | MRGPRX4CYP2D6CYP2C9MAPTALDH1A1 | |
| SCHEMBL901207 | 0.78 | TSHR (0.57) | MRGPRX4CYP2C9MAPTSRD5A2ALDH1A1 | |
| SCHEMBL2321634 | 0.78 | TSHR (0.57) | MRGPRX4CYP2C9MAPTSRD5A2ALDH1A1 | |
| SCHEMBL901209 | 0.78 | TSHR (0.57) | MRGPRX4CYP2C9MAPTSRD5A2ALDH1A1 | |
| SCHEMBL600741 | 0.76 | GPR119 (0.45) | MRGPRX4GPR119CYP2C9HCRTR2MAPT | |
| SCHEMBL600740 | 0.76 | GPR119 (0.45) | MRGPRX4GPR119CYP2C9HCRTR2MAPT | |
| Hydrochloric Acid SCHEMBL4290507 | 0.76 | TSHR (0.55) | MRGPRX4CYP2C9MAPTSRD5A2ALDH1A1 | |
| SCHEMBL11155303 | 0.74 | CYP2D6 (0.44) | MRGPRX4CYP2D6CYP2C9MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |