SCHEMBL27282986

SCHEMBL27282986

CC(C)CN1CCNC[C@H]1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
PIK3CD O00329 1/20 0.33
DPP4 P27487 1/20 0.32
DPP7 Q9UHL4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27281648 1.00 TDP1 (0.39) TDP1PIK3CDDPP4DPP7
SCHEMBL30340991 1.00 TDP1 (0.39) TDP1PIK3CDDPP4DPP7
Hydrochloric Acid SCHEMBL30341031 0.84 TDP1 (0.34) TDP1
SCHEMBL27067619 0.82 TDP1 (0.43) TDP1DPP4DPP7
SCHEMBL27284737 0.82 TDP1 (0.43) TDP1DPP4DPP7
SCHEMBL27282980 0.79 TDP1 (0.47) TDP1DPP4DPP7
SCHEMBL3101622 0.78 PIK3CD (0.32) TDP1PIK3CDDPP4
SCHEMBL12259539 0.78 PIK3CD (0.32) TDP1PIK3CDDPP4
SCHEMBL12259540 0.78 PIK3CD (0.32) TDP1PIK3CDDPP4
SCHEMBL27281651 0.78 TDP1 (0.37) TDP1DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 WO disclosed