SCHEMBL27282980

SCHEMBL27282980

CCCN1CCNCC1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
TAAR1 Q96RJ0 1/20 0.37
DPP4 P27487 1/20 0.32
DPP7 Q9UHL4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27284737 0.85 TDP1 (0.43) TDP1TAAR1DPP4DPP7
SCHEMBL27067619 0.85 TDP1 (0.43) TDP1TAAR1DPP4DPP7
SCHEMBL7285985 0.82 TDP1 (0.40) TDP1TAAR1
SCHEMBL7285992 0.82 TDP1 (0.40) TDP1TAAR1
SCHEMBL27282986 0.79 TDP1 (0.39) TDP1DPP4DPP7
SCHEMBL30340991 0.79 TDP1 (0.39) TDP1DPP4DPP7
SCHEMBL27281648 0.79 TDP1 (0.39) TDP1DPP4DPP7
SCHEMBL293011 0.78 TDP1 (0.45) TDP1TAAR1
SCHEMBL27748297 0.76 TDP1 (0.37) TDP1DPP4DPP7
SCHEMBL27281651 0.76 TDP1 (0.37) TDP1DPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 WO disclosed