Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892152 | 0.85 | MIF (0.43) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL11812711 | 0.80 | HTR2A (0.38) | HRH1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL6583 | 0.75 | MIF (0.63) | CHRM2ADRA1AMIFHTR2ATAAR1 | |
| SCHEMBL7980 | 0.75 | MIF (0.63) | CHRM2ADRA1AMIFHTR2ATAAR1 | |
| SCHEMBL211770 | 0.75 | MIF (0.63) | CHRM2ADRA1AMIFHTR2ATAAR1 | |
| SCHEMBL2729032 | 0.74 | SLC6A2 (0.48) | ADRA2BADRA1AOPRK1SLC6A3KCNH2 | |
| SCHEMBL21056125 | 0.74 | SLC6A2 (0.48) | ADRA2BADRA1AOPRK1SLC6A3KCNH2 | |
| SCHEMBL27515553 | 0.74 | SLC6A2 (0.48) | ADRA2BADRA1AOPRK1SLC6A3KCNH2 | |
| SCHEMBL5918667 | 0.74 | CYP3A4 (0.39) | HRH1CHRM2CHRM1ADRA2BADRA1A | |
| SCHEMBL4640624 | 0.74 | MIF (0.46) | HRH1MIFHTR2ATAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434884-B2 | Flame-retarding oligomeric brominated urethane compositions | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| EP-2632967-A1 | FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS | Lubrizol Advanced Materials, Inc. (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20130217286-A1 | FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012058538-A1 | FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |