SCHEMBL6583

SCHEMBL6583

CC(N=C=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.63
NOS2 P35228 1/20 0.44
ADRA2C P18825 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
ADRA2A P08913 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HSD11B1 P28845 4/20 0.38
CHRM2 P08172 1/20 0.38
ADRA1A P35348 1/20 0.38
RGS12 O14924 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211770 1.00 MIF (0.63) MIFNOS2ADRA2CKDM4ELMNA
SCHEMBL7980 1.00 MIF (0.63) MIFNOS2ADRA2CKDM4ELMNA
SCHEMBL27902285 0.94 MIF (0.57) MIFNOS2ADRA2CKDM4ELMNA
SCHEMBL23070416 0.94 MIF (0.57) MIFNOS2ADRA2CKDM4ELMNA
SCHEMBL443529 0.88 MIF (0.46) MIFNOS2CYP3A4
SCHEMBL28671467 0.88 MIF (0.50) MIFCYP2C9PKMCYP2C19
SCHEMBL22279429 0.88 MIF (0.50) MIFCYP2C9PKMCYP2C19
SCHEMBL7192060 0.84 MIF (0.45) MIFNOS2KDM4ELMNAHIF1A
SCHEMBL22265179 0.83 MIF (0.46) MIFADRA2CLMNAADRA2AALDH1A1
SCHEMBL22265178 0.83 MIF (0.46) MIFADRA2CLMNAADRA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306632-A Process for the preparation of isocyanate compounds comprising non-chlorinated derivatives and compositions thereof KS试验研究株式会社 2025-01-14 CN claimed
CN-119306631-A Process for the preparation of isocyanate compounds comprising non-chlorinated derivatives and compositions thereof KS试验研究株式会社 2025-01-14 CN claimed
CN-119161580-A Amide group-containing polydisulfide degradable high polymer material and preparation method thereof 衢州化工新材料创新研究院 2024-12-20 CN claimed
CN-114790163-B Glimepiride Process for the preparation of intermediates 江苏星诺医药科技有限公司 2024-08-27 CN claimed
US-20240154124-A1 NEGATIVE ELECTRODE PLATE AND LITHIUM-ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO., LTD. (CN) 2024-05-09 US claimed
US-11760750-B1 Process for preparing levoketoconazole NURAY CHEMICALS PRIVATE LIMITED (IN) 2023-09-19 US claimed
CN-115011053-B High-reflection fractal structure hydrogel, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-08-01 CN claimed
CN-116217444-A Photo-generated chiral radical molecule with circularly polarized luminescence property based on triarylamine derivative 中国科学院化学研究所 2023-06-06 CN claimed
US-20230151136-A1 CATALYST COMPOSITION FOR POLYURETHANES MOMENTIVE PERFORMANCE MATERIALS INC. 2023-05-18 US claimed
US-20230134280-A1 CATALYSTS FOR THE FORMATION OF POLYURETHANES MOMENTIVE PERFORMANCE MATERIALS INC. 2023-05-04 US claimed
EP-0566567-B1 ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES AMERICAN HOME PROD (US) 1997-11-19 EP claimed
US-5457212-A Process for the preparation of enantiomerically pure thienopyran derivatives ORTHO PHARMACEUTICAL CORPORATION (US) 1995-10-10 US claimed
EP-0566567-A1 ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-10-27 EP claimed
EP-0314446-B1 NOVEL ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-09-15 EP claimed
WO-1992012153-A1 NOVEL ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1992-07-23 WO claimed
EP-0493048-A1 The process for the preparation of enantiomerically pure thienopyran derivative ORTHO PHARMACEUTICAL CORPORATION (US) 1992-07-01 EP claimed
EP-0120428-B1 BENZOPYRAN ISOMERS BEECHAM GROUP PLC (GB) 1990-05-23 EP claimed
EP-0317085-A2 Processed red blood cells and process for producing the same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1989-05-24 EP claimed
EP-0314446-A2 Novel antihypertensive benzopyran derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1989-05-03 EP claimed
EP-0234353-A1 Process for the production of tetramethyl xylylene diisocyanates AMERICAN CYANAMID COMPANY (US) 1987-09-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760750-B1 Process for preparing levoketoconazole KHK, KYAT3, PLK3 MIF 2851/4885NOS2 3874/4885ADRA2C 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.