Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543968 | 0.91 | SLC6A3 (0.69) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL1903 | 0.90 | CYP3A4 (0.70) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9863980 | 0.88 | SLC6A3 (0.55) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9863852 | 0.87 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9864683 | 0.87 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9864029 | 0.86 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9863842 | 0.85 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9864283 | 0.85 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9863864 | 0.84 | SLC6A3 (0.68) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 | |
| SCHEMBL9863831 | 0.84 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1012733-B | Process for the preparation of therapeutic agents | BOOTS CO PLC (GB) | 1991-06-05 | — | — | CN | disclosed |
| CN-86100954-A | The preparation method of therapeutical agent and application | — | 1986-09-03 | — | — | CN | disclosed |