Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.33 |
| ▸ | CPT1A | P50416 | 5/20 | 0.32 |
| ▸ | CPT2 | P23786 | 3/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728516 | 0.91 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1HCRTR2HCRTR1 | |
| SCHEMBL6468130 | 0.90 | BACE1 (0.35) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL2727883 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2TRPV1CPT1ACPT2CPT1B | |
| Fumaric Acid SCHEMBL2732857 | 0.87 | BACE1 (0.33) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL6467725 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL2727131 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL2725565 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL2725564 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL2725797 | 0.82 | TRPV1 (0.35) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A | |
| SCHEMBL6467109 | 0.82 | TRPV1 (0.35) | SMN1; SMN2TRPV1HCRTR2HCRTR1CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |