Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29011975 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FFAR3LCK | |
| Acetic Acid SCHEMBL28767597 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FFAR3LCK | |
| SCHEMBL322669 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL28155621 | 0.90 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL10402585 | 0.88 | — | — | |
| Ethylene SCHEMBL6951144 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL9313077 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| Ethylene SCHEMBL6674101 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| Ethylene Glycol SCHEMBL1409004 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| Glycine SCHEMBL27933753 | 0.83 | GLRA1 (0.53) | ALDH1A1LMNAHSD17B10FFAR3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107758751-B | A kind of preparation method of resistance slurry ruthenic oxide | 潮州三环（集团）股份有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-107758751-A | A kind of preparation method of resistance slurry ruthenic oxide | 潮州三环（集团）股份有限公司 | 2018-03-06 | — | — | CN | claimed |
| CN-106470968-A | The method preparing 1,1 disubstituted vinyl monomers | 艾费尼蒂卡科技有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-101313426-B | Compliant seal structure for protected active metal anodes | POLYPLUS BATTERY CO INC | 2012-12-12 | — | — | CN | claimed |
| CN-100496472-C | Topical compositions and methods for treating pain | EPICEPT CORP (US) | 2009-06-10 | — | — | CN | claimed |
| CN-1747719-A | Topical compositions and methods for treating pain | EPICEPT CORP (US) | 2006-03-15 | — | — | CN | claimed |
| CN-1230939-C | Non-aqueous electrolyte secondary cell | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2005-12-07 | — | — | CN | claimed |
| CN-1443382-A | Non-aqueous electrolyte secondary cell | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2003-09-17 | — | — | CN | claimed |
| CN-107112084-B | Insulated wire and varnish for forming insulating layer | 住友电气工业株式会社 | 2019-11-15 | — | — | CN | disclosed |
| CN-107758751-B | A kind of preparation method of resistance slurry ruthenic oxide | 潮州三环（集团）股份有限公司 | 2019-05-17 | — | — | CN | disclosed |
| CN-105047540-B | Anti-reflecting layer and method | 台湾积体电路制造股份有限公司 | 2018-05-25 | — | — | CN | disclosed |
| CN-107758751-A | A kind of preparation method of resistance slurry ruthenic oxide | 潮州三环（集团）股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107474001-A | A kind of synthetic method of α diethyls acyloxymethyl substituted nitrogen heterocycle compounds | 河南师范大学 | 2017-12-15 | — | — | CN | disclosed |
| CN-107417818-A | It is a kind of for the catalytic component of olefinic polymerization, preparation method and catalyst | 北京利和知信科技有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-1554650-A | Process for the preparation of vialoguestamin d analogs | - | 2004-12-15 | — | — | CN | disclosed |
| CN-1508634-A | Toner and image-forming device using same | ������������ʽ���� | 2004-06-30 | — | — | CN | disclosed |
| CN-1443382-A | Non-aqueous electrolyte secondary cell | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2003-09-17 | — | — | CN | disclosed |
| CN-1334614-A | Non-aqueous electrolyte secondary cell | JAPAN STORAGE BATTERY CO LTD (JP) | 2002-02-06 | — | — | CN | disclosed |
| CN-1287115-A | Process for preparing vitamin D analogues | HOFFMANN LA ROCHE (CH) | 2001-03-14 | — | — | CN | disclosed |
| CN-1003937-B | NOVEL POLYMER AND CURED PRODUCT OF THE SAME | 钟渊化学工业株式会社 | 1989-04-19 | — | — | CN | disclosed |