Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018058 | 0.87 | HSD17B10 (0.57) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL27286146 | 0.86 | MAOB (0.47) | KDM4EALDH1A1LMNAKLKB1MAOB | |
| SCHEMBL12003036 | 0.84 | MAOB (0.51) | KLKB1MAOBBTK | |
| SCHEMBL17685622 | 0.83 | KLKB1 (0.46) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL27395839 | 0.83 | KLKB1 (0.46) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL30736811 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1LMNAKLKB1SMN1; SMN2 | |
| SCHEMBL8209503 | 0.83 | KLKB1 (0.45) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL31591076 | 0.82 | KLKB1 (0.51) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL17696410 | 0.81 | KLKB1 (0.55) | KDM4EALDH1A1LMNAKLKB1HSD17B10 | |
| SCHEMBL20531634 | 0.81 | KLKB1 (0.47) | KLKB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |