Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.95 |
| ▸ | HTR2C | P28335 | 15/20 | 0.95 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.95 |
| ▸ | DRD2 | P14416 | 1/20 | 0.95 |
| ▸ | HTR1A | P08908 | 1/20 | 0.79 |
| ▸ | DRD1 | P21728 | 1/20 | 0.79 |
| ▸ | DRD4 | P21917 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.79 |
| ▸ | CCR3 | P51677 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288366 | 1.00 | HTR2A (0.95) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| SCHEMBL27288363 | 0.99 | HTR2A (0.93) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| SCHEMBL27290546 | 0.99 | HTR2A (0.93) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL29355930 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL22067597 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL17681371 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL1468226 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL21524899 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL7996531 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A | |
| Lumateperone SCHEMBL5513940 | 0.97 | HTR2A (1.00) | HTR2AHTR2CSLC6A4DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145659-A1 | HETEROCYCLE FUSED GAMMA-CARBOLINES ACTING ON THE SEROTONINE 5-HT2A RECEPTOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2024-07-04 | — | — | WO | disclosed |