Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MYC | P01106 | 1/20 | 0.61 |
| ▸ | MAX | P61244 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18019597 | 1.00 | MAPT (0.68) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL27290720 | 0.89 | MAPT (0.60) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL28034505 | 0.82 | CRHBP (0.70) | MEN1KMT2ACRHBPCRHR2HTT | |
| SCHEMBL3301579 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL19035601 | 0.81 | MAPT (0.60) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL27290804 | 0.81 | CRHBP (0.65) | MAPTCRHBPCRHR2HTTLMNA | |
| SCHEMBL3888170 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL3888173 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL15679282 | 0.79 | MAPT (0.60) | MAPTMEN1KMT2AMYCMAX | |
| SCHEMBL27290775 | 0.79 | CRHBP (0.62) | MEN1KMT2ACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049236-A1 | CHIRAL GAMMA LACTAM DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PREPARATION METHOD THEREFOR | 고려대학교 산학협력단 | 2024-03-07 | — | — | WO | disclosed |