Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700164 | 1.00 | MGLL (0.64) | MGLLFAAHTRPV1SCN3AOPRK1 | |
| SCHEMBL27290848 | 0.83 | MGLL (0.47) | MGLLFAAH | |
| SCHEMBL27290308 | 0.82 | MGLL (0.43) | MGLLFAAHTRPV1 | |
| SCHEMBL30700152 | 0.82 | MGLL (0.43) | MGLLFAAHTRPV1 | |
| SCHEMBL30700176 | 0.79 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL30700009 | 0.79 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL30700174 | 0.79 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL27289695 | 0.79 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL30700147 | 0.79 | MGLL (0.46) | MGLLFAAH | |
| SCHEMBL27289691 | 0.79 | MGLL (0.46) | MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |