Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 6/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728568 | 1.00 | ITGB3 (0.58) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL2729462 | 0.89 | KLK5 (0.51) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL2729305 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL10278618 | 0.86 | ACE (0.59) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL2729283 | 0.86 | ACE (0.57) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL12835440 | 0.86 | ACE (0.58) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL7856016 | 0.85 | ACE (0.62) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL10890972 | 0.84 | ITGB3 (0.61) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL24725329 | 0.83 | ACE (0.65) | ITGB3ITGA2BACECTSSCTSK | |
| SCHEMBL3501896 | 0.83 | ACE (0.65) | ITGB3ITGA2BACECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058325-A1 | COMPOUNDS AND METHODS USEFUL FOR TREATMENT OF DISEASES MEDIATED BY HIF-1 | ONCOTHYREON INC. (US) | 2012-05-03 | — | — | WO | disclosed |