Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729478 | 0.93 | GPR119 (0.36) | GPR119CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL2729751 | 0.90 | GPR119 (0.48) | GPR119CSF1RKDR | |
| SCHEMBL15234150 | 0.89 | GPR119 (0.31) | GPR119 | |
| SCHEMBL2717412 | 0.88 | GPR119 (0.36) | GPR119CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL3695835 | 0.85 | GPR119 (0.47) | GPR119 | |
| SCHEMBL2729753 | 0.84 | GPR119 (0.48) | GPR119CSF1RKDR | |
| SCHEMBL15234148 | 0.83 | GPR119 (0.31) | GPR119 | |
| SCHEMBL2716117 | 0.79 | GPR119 (0.48) | GPR119CSF1RKDR | |
| SCHEMBL2718006 | 0.79 | GPR119 (0.48) | GPR119CSF1RKDR | |
| SCHEMBL2716115 | 0.79 | GPR119 (0.48) | GPR119CSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |