Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791596 | 1.00 | PTGS1 (0.55) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL1900173 | 1.00 | PTGS1 (0.55) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL27727592 | 0.90 | PTGS1 (0.48) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL8144491 | 0.90 | PTGS1 (0.48) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL3235657 | 0.90 | PTGS1 (0.48) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL15449455 | 0.90 | PTGS1 (0.48) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL346616 | 0.86 | PTGS1 (0.71) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL31202752 | 0.85 | PTGS1 (0.44) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL18913246 | 0.85 | PTGS1 (0.44) | PTGS1FFAR3LCKFYNAKR1C3 | |
| SCHEMBL10109999 | 0.85 | PTGS1 (0.44) | PTGS1FFAR3LCKFYNAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9177773-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| US-9177773-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150053854-A1 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-20150053854-A1 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-8853621-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853621-B2 | Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum | WAYNE STATE UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20140027631-A1 | Systems and Methods Extending the Laserspray Ionization Mass Spectrometry Concept from Atmospheric Pressure to Vacuum | WAYNE STATE UNIVERSITY (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140027631-A1 | Systems and Methods Extending the Laserspray Ionization Mass Spectrometry Concept from Atmospheric Pressure to Vacuum | WAYNE STATE UNIVERSITY (US) | 2014-01-30 | — | — | US | disclosed |
| US-8445533-B2 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| WO-2012058248-A2 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012058248-A2 | SYSTEMS AND METHODS EXTENDING THE LASERSPRAY IONIZATION MASS SPECTROMETRY CONCEPT FROM ATMOSPHERIC PRESSURE TO VACUUM | WAYNE STATE UNIVERSITY (US) | 2012-05-03 | — | — | WO | disclosed |
| EP-1817024-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| WO-2006101538-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| US-5708168-A | FOR TREATING OR PREVENTING NEURONAL LOSS | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) | 1998-01-13 | — | — | US | disclosed |
| WO-1996015112-A1 | AZEPINE SYNTHESIS VIA A DIELS-ALDER REACTION | ACEA PHARMACEUTICALS, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
| US-5476933-A | Condensation, ring expansion | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 1995-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | HAVCR2, MAVS, EIF2AK2 | PTGS1 1661/4885FFAR3 2123/4885LCK 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.