SCHEMBL27295795

SCHEMBL27295795

Cn1cnnc1-c1cnn(C)c1-c1cc(NC2(CC#N)CC2)nc(N2Cc3c(cc(CN4CCC5(CC5)C4)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27296296 0.91 CBLB (0.51) CBLB
SCHEMBL27318557 0.90 CBLB (0.52) CBLB
SCHEMBL27294820 0.90 CBLB (0.52) CBLB
SCHEMBL27327742 0.90 CBLB (0.48) CBLB
SCHEMBL27293162 0.89 CBLB (0.49) CBLB
SCHEMBL27294116 0.89 CBLB (0.51) CBLB
SCHEMBL27328610 0.89 CBLB (0.47) CBLB
SCHEMBL30349371 0.89 CBLB (0.55) CBLB
SCHEMBL30956931 0.88 CBLB (0.55) CBLB
SCHEMBL27292816 0.88 CBLB (0.55) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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