Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716463 | 0.90 | GPR119 (0.54) | GPR119PIK3CD | |
| SCHEMBL2716461 | 0.90 | GPR119 (0.54) | GPR119PIK3CD | |
| SCHEMBL2718743 | 0.90 | GPR119 (0.54) | GPR119PIK3CD | |
| SCHEMBL2716251 | 0.89 | GPR119 (0.47) | GPR119PIK3CDCYP2C9 | |
| SCHEMBL15233983 | 0.88 | GPR119 (0.36) | GPR119PIK3CD | |
| SCHEMBL15234222 | 0.88 | GPR119 (0.36) | GPR119PIK3CD | |
| SCHEMBL15233981 | 0.88 | GPR119 (0.36) | GPR119PIK3CD | |
| SCHEMBL15234224 | 0.88 | GPR119 (0.36) | GPR119PIK3CD | |
| SCHEMBL2717830 | 0.83 | GPR119 (0.47) | GPR119CYP2C9 | |
| SCHEMBL15234153 | 0.81 | GPR119 (0.57) | GPR119PIK3CDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | claimed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | claimed |
| EP-2445904-A1 | NOVEL GPR 119 AGONISTS | Cadila Healthcare Limited (IN) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010146605-A1 | NOVEL GPR 119 AGONISTS | CADILA HEALTHCARE LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |